Methamphetamine
Methamphetamine is an addictive stimulant drug that strongly
activates certain systems in the brain. Methamphetamine is closely
related chemically to amphetamine, but the central nervous system
effects of methamphetamine are greater. Both drugs have some medical
uses, primarily in the treatment of obesity, but their therapeutic
use is limited.
Methamphetamine is made in illegal laboratories and has a high
potential for abuse and dependence. Street methamphetamine is
referred to by many names, such as "speed," "meth," and "chalk."
Methamphetamine hydrochloride, clear chunky crystals resembling ice,
which can be inhaled by smoking, is referred to as "ice," "crystal,"
and "glass."
Methamphetamine Health Hazards
Methamphetamine releases high levels of the neurotransmitter
dopamine, which stimulates brain cells, enhancing mood and body
movement. It also appears to have a neurotoxic effect, damaging
brain cells that contain dopamine and serotonin, another
neurotransmitter. Over time, methamphetamine appears to cause
reduced levels of dopamine, which can result in symptoms like those
of Parkinson's disease, a severe movement disorder.
Methamphetamine is taken orally or intra-nasally (snorting the
powder), by intravenous injection, and by smoking. Immediately after
smoking or intravenous injection, the methamphetamine user
experiences an intense sensation, called a "rush" or "flash," that
lasts only a few minutes and is described as extremely pleasurable.
Oral or intranasal use produces euphoria - a high, but not a rush.
Users may become addicted quickly, and use it with increasing
frequency and in increasing doses.
Animal research going back more than 20 years shows that high
doses of methamphetamine damage neuron cell-endings. Dopamine- and
serotonin-containing neurons do not die after methamphetamine use,
but their nerve endings ("terminals") are cut back and re-growth
appears to be limited.
The central nervous system (CNS) actions that result from taking
even small amounts of methamphetamine include increased wakefulness,
increased physical activity, decreased appetite, increased
respiration, hyperthermia, and euphoria. Other CNS effects include
irritability, insomnia, confusion, tremors, convulsions, anxiety,
paranoia, and aggressiveness. Hyperthermia and convulsions can
result in death.
Methamphetamine causes increased heart rate and blood pressure
and can cause irreversible damage to blood vessels in the brain,
producing strokes. Other effects of methamphetamine include
respiratory problems, irregular heartbeat, and extreme anorexia. Its
use can result in cardiovascular collapse and death.
A study in Seattle confirmed that methamphetamine use was
widespread among the city's homosexual and bisexual populations. Of
these groups, members using methamphetamine reported they practice
sexual and needle-use behaviours that place them at risk of
contracting and transmitting HIV and AIDS.
Methamphetamine Extent of Use
Monitoring the Future Study (MTF)*
MTF assesses the extent of drug use among adolescents (8th-,
10th-, and 12th-graders) and young adults across the country. Recent
data from the survey:
- In 1997, 4.4 percent of high school seniors had used crystal
methamphetamine at least once in their lifetimes - an increase
from 2.7 percent in 1990.
- Data show that 2.3 percent of seniors reported past year use
of crystal methamphetamine in 1997 - an increase from 1.3
percent in 1990.
Community Epidemiology Work Group (CEWG)**
Methamphetamine is the dominant illicit drug problem in San
Diego. San Francisco and Honolulu also have substantial
methamphetamine- using populations. Patterns of increasing use have
been seen in Denver, Los Angeles, Minneapolis, Phoenix, Seattle, and
Tucson. New trafficking patterns have increased availability of the
drug in Missouri, Nebraska, and Iowa.
National Household Survey on Drug Abuse (NHSDA)
According to the 1996 NHSDA, 4.9 million people (aged 12 and
older) had tried methamphetamine at least once in their lifetimes
(2.3 percent of population). This is not a statistically significant
increase from 4.7 million people (2.2 percent) who reported using
methamphetamine at least once in their lifetime in the 1995 NHSDA.
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